Freeze and boost: new combo aims to stop Triple-Negative breast cancer return

NCT ID NCT03546686

First seen Oct 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study is for women with early-stage triple-negative breast cancer who still have tumor after initial chemotherapy. Researchers are testing a combination of a freezing treatment (cryoablation) and an immunotherapy drug given before surgery. The goal is to see if this approach can lower the chance of the cancer coming back over three years. About 51 women will take part.

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Contacts and locations

Locations

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Ohio State University Medical Center

    Columbus, Ohio, 43210, United States

  • Providence Cancer Institute

    Portland, Oregon, 97213, United States

  • UT Southwestern Medical Center

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.