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Freeze and fight: new combo tackles spread bladder cancer

NCT ID NCT04701918

First seen Jan 07, 2026 · Last updated May 24, 2026 · Updated 26 times

Summary

This study tested a two-step approach for people with advanced bladder cancer that has spread. First, doctors freeze some tumors (cryoablation), then give an immunotherapy drug (pembrolizumab or avelumab) to help the immune system attack remaining cancer. Only 9 people took part, and the goal was to see if tumors outside the frozen area shrank. The treatment aims to control the disease, not cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.