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Can cutting immune drugs boost vaccine power in transplant patients?

NCT ID NCT05077254

First seen Jan 11, 2026 · Last updated May 24, 2026 · Updated 17 times

Summary

This study looked at 48 kidney and liver transplant recipients who had a weak antibody response after their initial COVID-19 vaccines. Researchers gave them an extra vaccine dose, and for some, they temporarily reduced the patients' immune-suppressing medications to see if that would improve antibody levels. The goal was to find a safer way to better protect these high-risk patients from severe COVID-19.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Emory Healthcare

    Atlanta, Georgia, 30322, United States

  • Houston Methodist

    Houston, Texas, 77030, United States

  • Johns Hopkins Institute for Clinical and Translational Research: Broadway Adult Outpatient Clinical Research Unit

    Baltimore, Maryland, 21287, United States

  • Mt. Sinai Hospital

    New York, New York, 10029, United States

  • NYU Langone Transplant Institute

    New York, New York, 10016, United States

  • Northwestern University

    Evanston, Illinois, 60208, United States

  • Ochsner Health

    New Orleans, Louisiana, 70121, United States

  • University of California San Francisco Health

    San Francisco, California, 94143, United States

  • University of California, San Diego

    San Diego, California, 92093, United States

  • University of Illinois Health

    Chicago, Illinois, 60612, United States

  • University of Iowa Hospitals

    Iowa City, Iowa, 52242, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15260, United States

  • University of Wisconsin-Madison

    Madison, Wisconsin, 53706, United States

  • Weill Cornell Medicine

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.