Gene study seeks clues to Longer-Lasting kidney transplants
NCT ID NCT02555566
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether certain gene variations affect how well a transplanted kidney works over time. Researchers checked 80 kidney transplant recipients for specific gene markers and measured their kidney function for up to three years. The goal was to find clues that could help improve long-term transplant success.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
80 people
The number who actually took part.
- Start date
-
Mar 2014
- Finished
-
Dec 2016
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 75 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient aged 18 to 75 yo * Caucasian (because of different CYP epoxygenase polymorphisms) * First kidney transplantation performed in Rouen University Hospital after 2000, and at least 12 months before inclusion * Patient having read, understood and approved the informed consent * Efficient contraception in child-bearing aged women * Regular health insurance Exclusion Criteria: * Primary non-function, or allograft loss before 1 year * Previous kidney transplantation * History of psychiatric, psychologic or sensorial disorder preventing the patient from correctly understanding the protocol * History of bilateral arm or forearm arteriovenous fistula * Counter-indication to trinitrin * Insufficient understanding of written or spoken French language * Liberty-deprived patient * Pregnancy or absence of contraception in child-bearing aged women * Patient enrolled in another research protocol within 2 weeks before inclusion
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Chronic allograft nephropathy are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Rouen University Hospital
Rouen, 76031, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a vaccine protect the most vulnerable? a study probes immune response in transplant patients
- Could a common diabetes drug protect transplanted kidneys?
- Could a diabetes drug duo protect transplanted kidneys?
- Laser gum treatment shows promise for kidney transplant patients
- Could vitamins a and B3 shield kidney transplant patients from skin cancer?
- Personalized antibiotic strategy aims to prevent deadly infections after kidney transplant