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Should you get your COVID and flu shots together? new study aims to find out for the immunocompromised

NCT ID NCT06599658

First seen Mar 11, 2026 · Last updated Jun 22, 2026 · Updated 16 times

Summary

This study looks at whether giving the COVID-19 booster and flu vaccine at the same time is as good as giving them a month apart for people with weakened immune systems. It also tests if getting a COVID-19 booster every 3 months works better than every 6 months. About 660 adults with conditions like rheumatoid arthritis, HIV, or organ transplants will participate. Researchers will measure immune response through blood samples and track side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre hospitalier de l'Université de Montréal (CHUM)

    RECRUITING

    Montreal, Quebec, H2X 0C1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Maisonneuve -Rosemont Installation

    RECRUITING

    Montreal, Quebec, H1T2M4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Research Institute of McGill University Health Centre

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

COVID-19 booster vaccine and seasonal influenza vaccine

What this could lead to

If successful, this could help doctors give vaccines more effectively to immunocompromised people, improving protection against COVID-19 and flu.

What could go wrong

This is a phase 2 trial, so results are still uncertain. The study focuses on immune response, not directly on preventing illness, and may not apply to all immunocompromised groups.

Conditions

The condition(s) this trial relates to.

COVID-19 inflammatory bowel disease influenza rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.