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Scientists uncover how the brain compensates for balance loss

NCT ID NCT04268615

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at why some people with chronic balance problems develop very fast eye movements that help them see clearly when moving their head. Researchers tested 12 patients and 12 healthy volunteers using virtual reality and head movements. The goal was to understand what triggers these rapid eye movements, which could lead to better therapies for dizziness and blurred vision.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help develop better rehabilitation strategies for people with chronic balance problems.
What could go wrong
This is a small, early-stage observational study with only 32 participants, so results may not apply broadly. It does not test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

Dec 2020

Finished

Mar 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * For all : * Age from 18 to 90 * Understanding of the experimental instructions * Informed Consent * For Patients : Bilateral vestibular hypofunction with regards to the criteria of the of the Barany Society A. Chronic vestibular syndrome with at least three of the following symptoms 1. Postural imbalance 2. Unsteadiness of gait 3. Movement-induced blurred vision or oscillopsia during walking or quick head/body movements 4. Worsening of postural imbalance or unsteadiness of gait in darkness and/or on uneven ground B. No symptoms while sitting or lying down under static conditions C. Bilaterally reduced or absent angular VOR function documented by * bilaterally pathological horizontal angular VOR gain \< 0.6, measured by the video-HIT5or scleral-coil technique and/or * reduced caloric response (sum of bithermal max. peak SPV on each side \< 6°/sec7)and/or * reduced horizontal angular VOR gain \< 0.1 upon sinusoidal stimulation on a rotatorychair (0.1 Hz, Vmax = 50°/sec). D. Not better accounted for by another disease \* For Healthy control No ENT or neurological disorders Exclusion Criteria: * Corrected Visual Acuity lower than 5/10 * Other conditions leading to oscillopsia or ataxia * Oculomotor palsy, ocular instability in primary position * Treatment that may affect ocular motility (psychotropes) * Cervical rachis pathology with instability * Cochlear Implants * Non-stabilized medical disease * Pregnant women * Patients under tutelage * Patient without social security

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Conditions

The condition(s) this trial relates to.

Bilateral Vestibulopathy hyperreflexia idiopathic bilateral vestibulopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bilateral vestibulopathy Healthy volunteers Reflex, abnormal

Contacts and locations

Locations

  • Hospices Civils de Lyon

    Bron, 69500, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.