Can a simple injection stop coughing during lung exams?
NCT ID NCT05072236
First seen Nov 19, 2025 · Last updated Jun 19, 2026 · Updated 23 times
Summary
This study tested whether giving lidocaine or alfentanil before inserting a bronchoscope (a tube used to examine the lungs) can prevent coughing during the procedure. 108 patients with lung tumors received one of these drugs or a placebo before the scope was inserted. Researchers measured cough severity and other vital signs to see which drug worked best.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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National Taiwan University Cancer Center Hospital
Taipei, Taiwan
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lidocaine and alfentanil
What this could lead to
If it works, this could point toward a simple way to reduce coughing during bronchoscopy, making the procedure safer and more comfortable.
What could go wrong
This is a small, completed study with 108 participants, so results may not apply to everyone. The drugs can cause side effects like low blood pressure or breathing problems.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.