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Which exercise works best for Runner's knee? new study aims to find out

NCT ID NCT07664566

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares core stability exercises versus proprioceptive (balance) training in 63 adults aged 18-40 with patellofemoral pain syndrome (runner's knee). Participants will be assigned to one of two exercise programs to see which better reduces pain and improves knee function over time. The goal is to identify the most effective exercise approach for this common knee condition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Core stability exercises and proprioceptive training
What this could lead to
If successful, this could show which type of exercise better relieves knee pain and improves daily function for people with patellofemoral pain syndrome.
What could go wrong
This is a small, early-stage trial with only 63 participants, so results may not apply to everyone. Exercise studies rely on participant effort, and outcomes may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 63 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * A confirmed diagnosis of Patellofemoral Pain Syndrome (PFPS) based on clinical and radiographic examination, with no evidence of other knee pathologies, as verified by an orthopaedic physician * Presence of unilateral PFPS for a minimum duration of three months, indicating a chronic condition * Age between 18 and 40 years, representing the typical symptomatic population affected by PFPS * Body Mass Index (BMI) less than 30 kg/m², ensuring exclusion of obesity as a confounding factor. * Report of increased anterior knee pain during at least two of the following patellofemoral stress-provoking activities: stair ascent or descent, squatting, kneeling, running, or prolonged sitting * A positive patellar grind test (Clarke's sign) confirming involvement of the patellofemoral joint Exclusion Criteria: * Presence of chronic pain conditions unrelated to Patellofemoral Pain Syndrome (PFPS) as Rheumatoid arthritis, Chronic neuropathic pain, chronic low back pain and knee and hip osteoarthritis. * Pregnancy or history of recent trauma affecting the pelvic or knee region * History of corticosteroid injection in the affected knee * Presence of ankle arthritis or gouty arthritis, which may alter lower-limb biomechanics * History of previous surgical intervention involving the lumbar spine, hip, knee, or foot * Presence of lower-limb structural deformities, including pes planus, knee valgus, or knee varus deformities

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Conditions

The condition(s) this trial relates to.

Pain patellofemoral pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Patellofemoral pain syndrome

How to take part

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  1. The official record

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    Open the record ↗

  2. A doctor treating you

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More trials for these conditions

Other studies related to the condition(s) this trial covers.