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Why do some smokers get lung disease? scientists hunt for genetic clues

NCT ID NCT00608764

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 27 times

Summary

This study looks at why some smokers develop chronic obstructive pulmonary disease (COPD) while others don't. Researchers are studying over 10,000 smokers and non-smokers to find genetic factors that may increase COPD risk. The goal is to better understand the disease, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ann Arbor VA Medical Center

    Ann Arbor, Michigan, 48105, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • HealthPartners Research Foundation

    Minneapolis, Minnesota, 55440, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21224, United States

  • Los Angeles Biomedical Research Institute

    Torrance, California, 90502, United States

  • Minneapolis VA Medical Center

    Minneapolis, Minnesota, 55417, United States

  • Morehouse School of Medicine

    Atlanta, Georgia, 30310, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • Reliant Medical Group

    Worcester, Massachusetts, 01608, United States

  • Temple University

    Philadelphia, Pennsylvania, 19140, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35249, United States

  • University of California at San Diego

    San Diego, California, 92103, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Texas Health Sciences Center at San Antonio

    San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.