Which sedative combo is best for stomach scope procedures?
NCT ID NCT07190612
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 35 times
Summary
This study tested three different drug combinations to sedate patients during upper gastrointestinal endoscopy (a scope procedure to examine the stomach and esophagus). 75 adults were randomly assigned to receive propofol plus either ketamine, dexmedetomidine, or midazolam. Researchers measured how quickly patients woke up and how well they were sedated. The goal is to find the safest and most effective sedation approach for routine endoscopic procedures.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Faculty of Medicine
Cairo, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
propofol combined with either ketamine, dexmedetomidine, or midazolam
What this could lead to
If successful, this could help doctors choose the best sedation method for upper GI endoscopy, leading to faster recovery and fewer side effects.
What could go wrong
This is a small, completed Phase 4 trial with only 75 participants, so results may not apply to all patients. The study compares existing drugs, not a new breakthrough.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.