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Which womb biopsy method works best? new study compares two common techniques

NCT ID NCT07349108

Knowledge-focused Sponsor: Sheikh Zayed Medical College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 126 women aged 30-60 with abnormal uterine bleeding to compare two methods of taking a womb lining sample: manual vacuum aspiration and dilatation and curettage. The goal was to see which method gives a better tissue sample for diagnosing the cause of bleeding, including cancer. Researchers also measured pain levels 24 hours after the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

126 people

The number who actually took part.

Started

Sep 2025

Expected to finish

Feb 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 60 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Females aged 30-60 years. * Patients presenting with abnormal uterine bleeding (AUB) as per operational definition. * Patients who provide informed consent to participate in the study. Exclusion Criteria: * Patients with known pregnancy, active pelvic infection, or untreated sexually transmitted infections as per medical records. * Patients with known coagulopathy, bleeding disorders, or currently on anticoagulant therapy. * Patients with a history of endometrial or cervical cancer, abnormal Pap smear, pelvic pathology, or current hormonal use for endometrial pathology. * Patients who have undergone surgical intervention involving the uterus in the past three months. * Patients with severe medical conditions that could interfere with the study outcomes or pose a risk during the procedure (e.g., severe cardiovascular disease, uncontrolled diabetes). * Patients with a history of severe allergic reactions to local anesthesia or NSAIDs were used in the study. * Patients with stenotic cervical ostium. * Females with malignancy undergoing chemotherapy or radiotherapy (as per medical records).

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Conditions

The condition(s) this trial relates to.

Dilatation, Pathologic Metrorrhagia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abnormal uterine bleeding

Contacts and locations

Locations

  • Sheikh Zayed Medical college/hospital

    Rahim Yar Khan, Punjab Province, 75000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.