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Which biopsy method is better for diagnosing uterine bleeding?

NCT ID NCT07366814

Knowledge-focused Sponsor: Gaziosmanpasa Research and Education Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two common biopsy methods—Pipelle and Karman cannula—for diagnosing abnormal uterine bleeding in 480 women. All participants received the same local anesthetic to ensure fair pain comparison. The goal was to see which method provides better tissue samples and a more comfortable experience.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

480 people

The number who actually took part.

Started

Jan 2026

Finished

Feb 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female participants aged 18 years or older * Abnormal uterine bleeding or postmenopausal bleeding requiring endometrial sampling * Ability to provide written informed consent * Eligible for office-based endometrial biopsy Exclusion Criteria: * Pregnancy * Active pelvic infection * Known cervical or endometrial cancer * Severe cervical stenosis preventing endometrial sampling * Known bleeding disorders or use of anticoagulant therapy that contraindicates biopsy * Inability or unwillingness to provide informed consent

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Conditions

The condition(s) this trial relates to.

Metrorrhagia Patient Satisfaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abnormal uterine bleeding Postmenopausal bleeding

Contacts and locations

Locations

  • University of Health Sciences, Gaziosmanpaşa Training and Research Hospital

    Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.