Could a simple additive make arm surgery Pain-Free longer?
NCT ID NCT06779604
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two common medications, dexmedetomidine and dexamethasone, when added to a nerve block for arm surgery. The goal is to see which one helps the block work faster, last longer, and reduce the need for painkillers afterward. About 44 adults aged 18-70 will take part, and researchers will track pain scores and side effects for 24 hours after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 44 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
A total of 44 adult patients 18 to 70 years, American Society of Anesthesiologists (ASA) I-II who underwent upper extremity surgery were included in Orthopedics and Traumatology Clinic.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18-70 years * ASA I-II Exclusion Criteria: * Under 18 years of age and older than 70 years of age, * presence of brachial plexus injury, * patients with bleeding diathesis, * presence of allergy, -contralateral diaphragmatic paralysis, - * presence of nerve injury secondary to trauma, * pre-existing neuropathy of the surgical extremity, * presence of severe pulmonary, * renal and hepatic disease, * congestive heart failure (NYHA stage 3-4), * uncontrolled diabetes mellitus, * history of neuromuscular disease, * patients with extreme obesity or malnutrition (BMI \> 30 kg-1m2 or BMI \<20 kg-1m2), * presence of epilepsy, * history of peripheral vascular disease, * history of chronic pain or fibromyalgia, * pregnant and lactating patients, * patients with local infection at the injection site, * patients undergoing general anesthesia due to inadequacy of the block, * patients refusing to give informed consent, * history of recreational substance use, and chronic narcotic-based painkillers
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Umraniye Education and Research Hospital
RECRUITINGIstanbul, Umraniye, 34034, Turkey (Türkiye)
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