New drug combo shows promise for Hard-to-Treat ovarian and endometrial cancers
NCT ID NCT05950464
First seen Sep 30, 2025 · Last updated Apr 29, 2026 · Updated 32 times
Summary
This early-phase study tests a combination of two experimental drugs (M1774 and ZEN-3694) in people whose ovarian or endometrial cancer has returned after previous treatment. The goal is to find the safest dose and see how well the drugs work together to stop cancer growth. About 60 adults will take part.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Augusta University Medical Center
RECRUITINGAugusta, Georgia, 30912, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Case Western Reserve University
ACTIVE_NOT_RECRUITINGCleveland, Ohio, 44106, United States
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Cleveland Clinic Foundation
RECRUITINGCleveland, Ohio, 44195, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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NRG Oncology
RECRUITINGPhiladelphia, Pennsylvania, 19103, United States
Contact Email: •••••@•••••
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Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Thomas Jefferson University Hospital
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Chicago Comprehensive Cancer Center
RECRUITINGChicago, Illinois, 60637, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Iowa/Holden Comprehensive Cancer Center
RECRUITINGIowa City, Iowa, 52242, United States
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Contact Phone: •••-•••-••••
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University of New Mexico Cancer Center
RECRUITINGAlbuquerque, New Mexico, 87106, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Oklahoma Health Sciences Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pennsylvania/Abramson Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Wayne State University/Karmanos Cancer Institute
RECRUITINGDetroit, Michigan, 48201, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Women and Infants Hospital
RECRUITINGProvidence, Rhode Island, 02905, United States
Contact
Contact Phone: •••-•••-••••
Conditions
Explore the condition pages connected to this study.