Platinum-resistant ovarian carcinoma
Clinical trials for Platinum-resistant ovarian carcinoma explained in plain language.
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New drug combo targets Hard-to-Treat ovarian and endometrial cancers
Disease control Recruiting nowThis early-phase trial is testing the safety and best dose of two drugs, M1774 and ZEN-3694, given together to patients with recurrent ovarian or endometrial cancer. The drugs work by blocking enzymes that cancer cells need to grow. The study aims to find a dose that is safe and …
Matched conditions: PLATINUM-RESISTANT OVARIAN CARCINOMA
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Immune cells retrained to hunt ovarian cancer in new trial
Disease control Recruiting nowThis phase 1 trial investigates a new treatment for advanced ovarian cancer that has stopped responding to platinum chemotherapy. The therapy uses a patient's own immune cells, called T cells, which are genetically modified in a lab to recognize and attack a protein called TAG72 …
Matched conditions: PLATINUM-RESISTANT OVARIAN CARCINOMA
Phase 1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Aug 19, 2026 00:00 UTC
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New hope for Platinum-Resistant ovarian cancer: ONC201 and paclitaxel combo trial launches
Disease control Recruiting nowThis Phase 2 trial tests whether adding the experimental drug ONC201 to standard chemotherapy (paclitaxel) can help women with ovarian, fallopian tube, or peritoneal cancer that has stopped responding to platinum-based treatments. About 62 participants will receive the combinatio…
Matched conditions: PLATINUM-RESISTANT OVARIAN CARCINOMA
Phase 2 • Sponsor: Ira Winer • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Supercharged immune cells take on tough ovarian cancers
Disease control Recruiting nowThis early-phase study tests a new treatment for people with ovarian cancer that has returned or is resistant to standard platinum chemotherapy. The treatment uses a patient's own immune cells (T cells), which are trained in a lab to recognize and attack a protein called MUC1 fou…
Matched conditions: PLATINUM-RESISTANT OVARIAN CARCINOMA
Phase 1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Old drug, new hope: atovaquone tested against tough ovarian cancer
Disease control Recruiting nowThis phase II trial tests whether atovaquone, a drug currently used to treat certain infections, can help control platinum-resistant ovarian cancer. The study enrolls 28 patients whose cancer has progressed within six months of their last platinum-based chemotherapy. Participants…
Matched conditions: PLATINUM-RESISTANT OVARIAN CARCINOMA
Phase 2 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 26, 2026 16:38 UTC