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New tool aims to curb opioid abuse by reminding doctors to check state database

NCT ID NCT06215560

Knowledge-focused Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a computer alert that pops up when a doctor prescribes an opioid or sedative, reminding them to check Colorado's prescription drug monitoring program (PDMP). The goal was to see if the alert helps doctors follow state law and reduce risky prescribing. Researchers tracked nearly 90,000 patient encounters across emergency rooms, clinics, and hospitals.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Clinical decision support tool (EHR alert)
What this could lead to
If successful, this tool could help doctors follow state laws and reduce risky prescribing of opioids and sedatives, potentially lowering overdose rates.
What could go wrong
This is an observational study of an informational tool, not a treatment. It may not change prescribing behavior or patient outcomes significantly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

89,871 people

The number who actually took part.

Started

Jan 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Residents and visitors to the state of Colorado who seek healthcare within the University of Colorado Health (UCHealth) system.

Ages

12 to 89 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion: Health care providers: 1\. Health care providers licensed to prescribe opioids, employed at UCHealth Emergency department, ambulatory care practices or inpatient settings within the UCHealth system. Patient encounters: 1. Patients seen in the UCHealth Emergency Department, outpatient clinic/office or inpatient setting during the intervention period 2. Provider initiates a prescription for an opioid or benzodiazepine 3. patient is between 12-89 years of age, inclusive Exclusion: Health care providers: 1. Providers primarily practicing in dentistry, veterinary medicine, oncology, pediatrics, palliative, or hospice practices. 2. Providers in ambulatory practices (primary care and specialty clinics) which write a total of less than 52 opioids and benzodiazepine prescriptions in the year prior to study initiation. Patient encounters: 1. Encounters in dentistry, veterinary medicine, oncology practices, pediatrics practices, palliative care or hospice practices 2. Prisoners or wards of the state 3. Age \<12 or \>89 YOA 4. Active diagnosis of sickle cell, cancer, or in hospice care.

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Conditions

The condition(s) this trial relates to.

substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Medication abuse

Contacts and locations

Locations

  • University of Colorado Hospital

    Aurora, Colorado, 80045, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.