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Brain training showdown: 1,600 volunteers test if puzzles boost memory

NCT ID NCT06375681

Knowledge-focused Sponsor: University of Wisconsin, Madison Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will enroll 1,600 healthy adults (ages 18-30 or 60-85) to see if doing computer-based cognitive tasks—like remembering sequences or spotting patterns—can improve memory, attention, and thinking skills. Participants will complete up to 15 hours of tasks over 4-8 weeks. The goal is to measure changes in working memory and cognitive flexibility, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cognitive tasks (visual and auditory exercises on a computer)
What this could lead to
If it works, this could show that simple computer-based brain exercises can improve memory and attention in healthy adults.
What could go wrong
This is an early-stage study with no direct health outcome—it measures changes in test scores, not real-world benefits. Results may not apply to everyone or lead to a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,600 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Self-reported normal or corrected-to-normal vision * No known neurological impairments * Age within inclusion range (18-30 Years for Younger Adults and 60-85 Years for Older Adults) Exclusion Criteria * Physical handicap (motor or perceptual) that would impede training procedures * Concurrent enrollment in other cognitive training studies * Not being proficient enough in English that would prevent following and understanding all instructions and completing all testing sessions (typically, participants would need to have learned English before age 11; there might be some exceptions that will be decided on a case-by-case basis). * Unable to adhere to training schedule Additional exclusion criteria for older adults: \- Score \< 17 (out of 22) on the Telephone Montreal Cognitive Assessment (T-MoCA).

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive change

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Northeastern University

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • University of California, Riverside

    RECRUITING

    Riverside, California, 92521, United States

  • University of Wisconsin - Madison

    RECRUITING

    Madison, Wisconsin, 53706, United States

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