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Digital brain training may ease 'chemo brain' — a trial puts it to the test

NCT ID NCT07729969

Symptom relief Sponsor: Biogipuzkoa Health Research Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial tests whether two types of home-based digital cognitive training can help cancer survivors who have memory, attention, or thinking problems after chemotherapy. Participants will use either a computer program (BrainHQ) or a virtual reality cognitive training for 10 weeks. The study compares these interventions to a control group to see which approach is most effective and user-friendly.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
computerized cognitive training via BrainHQ program
What this could lead to
If effective, this could offer a convenient, home-based way to ease cognitive difficulties after cancer treatment.
What could go wrong
This is a relatively small, early-stage trial. The cognitive benefits may be modest or not translate to real-world improvements.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 110 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over 18 years of age diagnosed with cancer (stage I-III) * Subjective complaints of cognitive functioning related to the diagnosis of cancer and/or cancer treatments * Between 1-6 months after completion of chemotherapy treatment * To have Wi-Fi and a computer/tablet * To sign the informed consent form Exclusion Criteria: * Previous history of cancer diagnosis * Anticipated change in cancer treatment/general medical treatment during the intervention period * Previous diagnosis of cognitive impairment * Diagnosis of other neurological or psychiatric diseases * Diagnosis of severe untreated depression * History of episodes of vertigo, epilepsy or seizures * Currently undergoing or having undergone any other type of intervention aimed at improving cognitive functioning (e.g., CRCI workshops) * Severe visual or hearing difficulties that may affect the performance of the intervention exercises * Inability to speak, understand, read, and write Spanish correctly * Failure to sign the informed consent form

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Conditions

The condition(s) this trial relates to.

cancer Cognitive Dysfunction neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer Cognitive change Cognitive impairment

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospital Universitario Basurto

    RECRUITING

    Bilbao, Bizkaia, 48013, Spain

  • Hospital Universitario Donostia

    RECRUITING

    San Sebastián, Gipuzkoa, 20014, Spain

  • Hospital Universitario Galdakao-Usansolo

    RECRUITING

    Galdakao, Bizkaia, 48960, Spain

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