Brain boost for blood cancer survivors: diet and games tested
NCT ID NCT05708716
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining a modified ketogenic diet (using a meal replacement drink) with online brain training can improve memory and thinking in blood cancer survivors. About 80 adults with mild to moderate cognitive issues will either get the combined program for 12 weeks or wait and then receive only the brain training. The goal is to see if this approach is practical and helps cognitive function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- modified ketogenic diet (KetoCal) and online cognitive training (Lumosity)
- What this could lead to
- If it works, this could offer a simple, non-drug way to help blood cancer survivors think more clearly and remember better.
- What could go wrong
- This is a small, early feasibility study with only 80 people. The diet and training may be hard to stick with, and benefits might not last or apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2022
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult with hematologic malignancy diagnosed at age ≥21 years * Outpatient at least 3 months from completion of blood or marrow transplant (BMT) or at least 6 months from diagnosis for patients not treated with BMT * Evidence of mild-to-moderate cognitive impairment using either the Modified Telephone Interview for Mild Cognitive Impairment (TICS-M) or PROMIS 8a short form raw score = 19 -37 * Have daily access to an internet-connected home computer * Can fluently read and write in English * Can understand and sign the study-specific Informed Consent Form Exclusion Criteria: * History of pre-existing neurological disorder or documented major psychiatric disorder * Significant auditory, visual, or motor impairments * History of color blindness * Participated in neuropsychological intervention within the past 6 months * Evidence of active chronic graft vs. host disease (GvHD) for allogeneic BMT * History of pre-existing metabolic disease * Allergies to soy or milk * Body Mass Index (BMI) ≤20
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
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