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Can Hands-On tinkering keep aging brains sharp?

NCT ID NCT05358145

NEW Prevention Sponsor: National Taiwan University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers are testing whether hands-on tinkering activities, which blend science, art, and technology, can improve cognitive flexibility in adults over 65. The trial compares tinkering with board games and a control activity over 12 weeks. Participants complete thinking tasks and brain wave recordings before and after to measure changes in mental flexibility.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Tinkering activities, hands-on science, art, and technology projects
What this could lead to
If tinkering activities help, they could offer a low-cost, engaging way for older adults to maintain cognitive flexibility and slow age-related mental decline.
What could go wrong
This is an early behavioral study with 118 participants. Cognitive training effects are often small and may not last, and results in a controlled setting may not translate to everyday life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

118 people

The number who actually took part.

Started

Feb 2021

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Literate in Mandarin and Taiwanese * Willing to participate entirely in this research. * Age \>65 Exclusion Criteria: * Participated in cognitive-related training in the past two months. * Severe impairment of visual or auditory abilities. * Diagnosed with mild cognitive impairment (MCI), or Dementia * Severe psychological or behavioral disorder that would seriously interfere with the progress of activity * History of degenerative cognitive disorder (e.g., acute stroke, traumatic brain injury, unconscious), organic mental disorders, brain dysfunction, or other neurology-related diagnoses.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive training

Contacts and locations

Locations

  • College of Medicine, National Taiwan University

    Taipei, 10051, Taiwan

  • National Taiwan Science Education Center

    Taipei, 11165, Taiwan

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