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Brain-Training games put to the test for slowing mental decline

NCT ID NCT07753382

Symptom relief Sponsor: China Medical University, China Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This study tests whether a 12-week program of adaptive computerized cognitive training—brain exercises that automatically adjust to each person's performance—can improve memory, attention, and other thinking skills in older adults with mild cognitive impairment. Participants, aged 60 and older, will use a WeChat mini-program to train on tasks targeting multiple cognitive areas. The trial compares two groups after the initial training: one that continues with high-frequency maintenance sessions and one that stops, to see if ongoing practice helps preserve any gains.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Adaptive computerized cognitive training delivered via a WeChat mini-program
What this could lead to
If effective, this could offer a practical, home-based way to help older adults with mild cognitive impairment maintain or improve their thinking skills.
What could go wrong
The trial is small and early, so results may not apply broadly. Cognitive training benefits often don't carry over to real-world tasks, and the effect may fade after training stops.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 36 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age \>= 60 years; 2. Planning to reside in the community for at least 12 months, with no intention to move into a nursing home; 3. No clinical diagnosis of dementia; 4. Meeting the diagnostic criteria for mild cognitive impairment (MCI) as defined in the Chinese Expert Consensus on the Diagnosis and Treatment of Alzheimer's Disease-Related Mild Cognitive Impairment (2021), The cut-off scores for the Beijing version of the Montreal Cognitive Assessment (MoCA) were adjusted for educational level: \<=13 for junior high school or below, \<=19 for high school, and \<=24 for college education or above. Mini-Mental State Examination (MMSE) score \>= 24; Activities of Daily Living (ADL) score \<23. 5. Able to use a mobile application (mini program) to perform cognitive training. Exclusion Criteria: 1. Individuals unable to complete the questionnaires due to hearing or visual impairments; 2. Those with other organic diseases of the central nervous system, such as brain tumors, epilepsy, or Parkinson's disease; 3. Those diagnosed with severe mental disorders, such as schizophrenia, depression, or anxiety disorders.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive dysfunction, cognitive disorder Cognitive training

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ren'ai Changwan Community Elderly Care Service Station, Dadong

    Shenyang, Liaoning, 110000, China

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