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Online brain games for dementia: new study tests if virtual therapy can keep minds sharp

NCT ID NCT05860127

Symptom relief Sponsor: University of Massachusetts, Amherst Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a virtual group therapy program called Cognitive Stimulation Therapy (V-CST) could help slow cognitive decline in people with mild to moderate dementia. 133 participants were randomly assigned to either receive a referral for V-CST or continue with standard care. The therapy involves online group activities designed to stimulate thinking and memory. The study focused on whether people would accept the referral and whether their cognitive scores changed over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Cognitive Stimulation Therapy (CST) - a group therapy program delivered online
What this could lead to
If it works, this could offer a non-drug way to help people with dementia maintain their thinking skills longer.
What could go wrong
This is a small pilot study (133 people) testing whether the approach is acceptable and practical, not whether it definitively works. Results may not apply to everyone with dementia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

133 people

The number who actually took part.

Started

Apr 2023

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of Mild Cognitive Impairment or Mild to Moderate Dementia * MoCA score of 10 to 26 OR SLUMS score of 10 to 26 OR MMSE score between 13 and 24 recorded as present \< 24 months before the record review * English-speaking * Visit scheduled to include cognitive screening 6 to 12 months after record review. Exclusion Criteria: * Auditory or visual impairment, combative behaviors, or other clinician-assessed condition that would interfere with group treatment * No access to online meeting platform * Patient has specified to HCS not to engage patient in research or to use patient data in research * Patient has previously participated in V-CST * Physician determines a caregiver is needed to support V-CST participation, but no caregiver available to assist with technology.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction dementia follicular lymphoma frontotemporal dementia Lewy body dementia Lewy Body Disease Mixed Dementias vascular dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive impairment, mild Dementia Dementia frontal Dementia moderate Dementia of Alzheimer type Dementia with lewy bodies Dementia, mild Dementia, mixed Dementia, vascular

Contacts and locations

Locations

  • UConn Center on Aging

    Farmington, Connecticut, 06030, United States

  • Yale Memory Clinic

    New Haven, Connecticut, 06536, United States

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