Can chewing gum beat a drug for nausea after surgery?
NCT ID NCT07201883
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether chewing gum can stop nausea and vomiting after laparoscopic surgery as well as the standard drug ondansetron. About 90 women will receive either gum, the drug, or both. The goal is to find a simple, drug-free option for relief.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- chewing gum (peppermint sugar free) and ondansetron (Zofran)
- What this could lead to
- If chewing gum works, it could offer a simple, low-cost way to ease post-surgery nausea without medication.
- What could go wrong
- This is a small, early-phase trial with only 90 women at one hospital. Results may not apply to other groups or surgeries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
-
About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Aug 2025
- Expected to finish
-
Feb 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Female participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Females * Aged 18 and above, * Weight 40kg and above, * Who have undergone laparoscopic * Surgery under volatile anesthetic-based general anesthesia. Exclusion Criteria: * Have history of motion sickness, * Maintained anesthesia during surgery using Propofol-pump * Were given antiemetics within 8 hours pre-surgery * Allergy to ondansetron * Planned mechanical ventilation post-operation
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Postoperative nausea and vomiting (PONV) are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Makassed General Hospital
Beirut, Lebanon
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Sinus surgery without opioids: can dexmedetomidine do the job?
- Can patient traits predict pain after heart surgery?
- Could a common Anti-Nausea drug help kids sleep better after surgery?
- New opioid aims to cut Post-Surgery nausea without sacrificing pain relief
- Could a common sedative stop post-surgery nausea?
- Ear zaps may cut opioid need after surgery