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Can chewing gum beat a drug for nausea after surgery?

NCT ID NCT07201883

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether chewing gum can stop nausea and vomiting after laparoscopic surgery as well as the standard drug ondansetron. About 90 women will receive either gum, the drug, or both. The goal is to find a simple, drug-free option for relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
chewing gum (peppermint sugar free) and ondansetron (Zofran)
What this could lead to
If chewing gum works, it could offer a simple, low-cost way to ease post-surgery nausea without medication.
What could go wrong
This is a small, early-phase trial with only 90 women at one hospital. Results may not apply to other groups or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Feb 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Females * Aged 18 and above, * Weight 40kg and above, * Who have undergone laparoscopic * Surgery under volatile anesthetic-based general anesthesia. Exclusion Criteria: * Have history of motion sickness, * Maintained anesthesia during surgery using Propofol-pump * Were given antiemetics within 8 hours pre-surgery * Allergy to ondansetron * Planned mechanical ventilation post-operation

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Conditions

The condition(s) this trial relates to.

Postoperative Nausea and Vomiting Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Makassed General Hospital

    Beirut, Lebanon

More trials for these conditions

Other studies related to the condition(s) this trial covers.