Simple chest squeeze may improve oxygen flow in ARDS patients
NCT ID NCT06699017
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study tested a technique called continuous anterior chest compression (CACC) in 20 adults with moderate to severe acute respiratory distress syndrome (ARDS). The goal was to see if manually pressing on the chest could improve how air and blood move through the lungs, and whether it affects heart function. Researchers used imaging to measure lung ventilation and blood flow, and ultrasound to check heart performance.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- manual continuous anterior chest compression
- What this could lead to
- If it works, this could point toward a simple, low-cost way to improve breathing and heart function in patients with severe lung injury.
- What could go wrong
- This is a very small, early study with only 20 participants, so results may not apply to all ARDS patients. The technique is manual and may be hard to standardize.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
20 people
The number who actually took part.
- Started
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Feb 2023
- Finished
-
Jun 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * ARDS moderate to severe according to the Berlin criteria * Patient receiving continuous sedation and curarization * Free and informed consent from the patient or family member Exclusion Criteria: * Pregnancy * Adult patient subject to a legal protection measure (tutor, curator, etc.) * Patients with a pacemaker, automatic implantable cardioverter defibrillator, * Contraindications to thoracic belt placement (e.g., thoracic or spinal cord trauma, recent thoracic surgery) * Undrained pneumothorax, bronchopleural fistula * Hemodynamic instability (i.e., use of intravenous fluids of more than 10 mL/kg or vasopressors 2 mg/h of norepinephrine or 0.5 mg/h of epinephrine)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Henri Mondor hospital
Créteil, Creteil, 94010, France
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Other studies related to the condition(s) this trial covers.
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