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Chair time in ICU may boost recovery for ventilated patients

NCT ID NCT06973746

Symptom relief Sponsor: Centre Hospitalier Régional d'Orléans Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether moving patients on breathing machines out of bed and into a chair helps them regain strength and function better than staying in bed. About 150 adults in the ICU will be randomly assigned to either chair sitting or bed rest. The goal is to see if chair positioning improves muscle recovery and mobility by the time they leave the ICU.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Jan 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patient \> 18 years old 2. Patient on invasive mechanical ventilation for more than 24 hours 3. Patient in recovery phase with a RASS score greater than "-3" for more than 12 hours 4. Stay expected to last 48 hours 5. Patient has never been placed in a chair during this hospitalization in intensive care. 6. Fragility score \< 6, during the month preceding admission to intensive care 7. Patient (or support person/relative if patient is unable to participate) who has agreed to take part in the study. Exclusion Criteria: 1. Patient with an absolute and non-resolving contraindication to chair positioning 1. Fracture or orthopedic disorder contraindicating mobilization out of bed 2. Obesity with body mass index greater than 45 kg/cm2 3. Sacral eschar stage greater than 2 2. Patient using a wheelchair for mobility (i.e. paraplegic patient or patient with progressive neurological pathology). 3. Patient treated with veno-venous or veno-arterial ECMO at the time of screening. 4. Moribund patient 5. Encephalic death 6. Acute polyradiculoneuritis (Guillain-Barré syndrome) 7. Myasthenia 8. Patient treated by continuous hemodialysis or hemofiltration for more than 72 hours following the onset of awakening. 9. Complete transmetatarsal or higher amputation of one or both lower limbs. 10. Protected person (under guardianship or curatorship) 11. Person under court protection 12. Person not affiliated to a social security scheme 13. Pregnant or breast-feeding woman 14. Patient already included in the study 15. Patient taking part in an interventional clinical study, the aim of which is to show an improvement in functional level on discharge from the intensive care unit or which focuses on the theme of early rehabilitation in the intensive care unit.

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Conditions

The condition(s) this trial relates to.

critical illness polyneuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Icu acquired weakness

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    11 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CH Chartres

    RECRUITING

    Le Coudray, 28630, France

  • CH de DAX

    NOT_YET_RECRUITING

    Dax, 40100, France

  • CH de Saint-Lô

    NOT_YET_RECRUITING

    Saint-Lô, France

  • CHI Mont de Marsan

    RECRUITING

    Mont-de-Marsan, 40012, France

  • CHRU de TOURS

    RECRUITING

    Tours, France

  • CHU Clermont Ferrand

    RECRUITING

    Clermont-Ferrand, France

  • CHU de DIJON

    RECRUITING

    Dijon, France

  • Centre Hospitalier Universitaire d'Orléans

    RECRUITING

    Orléans, Centre-Val de Loire, 45067, France

  • Ch Du Mans

    RECRUITING

    Le Mans, 72037, France

  • Hopital Foch

    NOT_YET_RECRUITING

    Suresnes, France

  • Hopital Nord Franche Comte

    RECRUITING

    Belfort, France

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