Can a simple ultrasound replace CT scans for detecting internal bleeding after trauma?
NCT ID NCT05627908
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a special ultrasound (CEUS) can find hidden bleeding pockets (pseudoaneurysms) in the liver, spleen, or kidneys after an injury, just as well as the standard CT scan. About 385 adults with abdominal trauma will be followed over time with both tests. If CEUS proves reliable, it could reduce the need for repeated CT scans and radiation exposure.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 385 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2022
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
adult patients (18 years old and above) with proven blunt or penetrating splenic and/or liver and/or renal trauma as shown by a CT scan and classified according to the American Injury Scale American Association for Surgery (AAST) Organ Injury Scale (OIS) will be included
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * adult patients (18 years old and above) with proven blunt or penetrating splenic and/or liver and/or renal trauma as shown by a CT scan and classified according to the American Injury Scale American Association for Surgery (AAST) Organ Injury Scale (OIS) will be included Exclusion Criteria: * minor to 18 years old
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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ASST GOM Niguarda
RECRUITINGMilan, Italia, 20162, Italy
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