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New study aims to improve cervical cancer monitoring for HIV-Positive women

NCT ID NCT07202936

Knowledge-focused Sponsor: University of Bern Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study follows 168 women living with HIV in Zimbabwe who have been treated for cervical pre-cancer. Researchers want to learn how often the disease comes back and whether HPV or DNA tests can predict recurrence. Participants will be monitored every six months for two years with biopsies and cervical samples.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better guidelines for monitoring cervical pre-cancer in women with HIV, reducing recurrence and cancer risk.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may not apply to other countries or populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

168 people

The number who actually took part.

Started

May 2024

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Women living with HIV who are high-risk HPV positive and need cervical pre-cancer treatment

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged 18-65 years * Positive HIV status confirmed through medical records * Positive test result for any high-risk HPV genotype at preceding cervical cancer screening visit * Cervical pre-cancer treatment required according to Newlands Clinic guidelines * Signed informed consent Exclusion Criteria: * Women with a history or suspicion of cervical cancer * Women with a history of total hysterectomy (no cervix) * Women treated for cervical pre-cancer in the past 12 months * Pregnant women

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Conditions

The condition(s) this trial relates to.

cervical intraepithelial neoplasia HIV infectious disease human papilloma virus infection Uterine Cervical Neoplasms uterine cervix neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV I infection HPV infection Uterine cervical neoplasms

Contacts and locations

Locations

  • Women's Health Centre at Newlands Clinic

    Harare, Zimbabwe

More trials for these conditions

Other studies related to the condition(s) this trial covers.