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Can a zapping the brain ease fibromyalgia pain?

NCT ID NCT05963321

Symptom relief Sponsor: Hospital de Clinicas de Porto Alegre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a single session of mild electrical brain stimulation (tDCS) over the cerebellum can help reduce pain in women with fibromyalgia. About 92 right-handed women aged 18-65 with confirmed fibromyalgia and moderate-to-severe pain will receive the stimulation. The goal is to see if this approach can temporarily ease pain and change how the brain processes pain signals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 92 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2023

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Right-handed women aged 18 to 65 years; who can read and write * Confirmed diagnosis of fibromyalgia according to the criteria of the American College of Rheumatology (2010-2016). * Pain score equal to or greater than 4 on the Numerical Pain Scale (Score 0-10) on most days in the last 3 months. Exclusion Criteria: * Reside outside Porto Alegre area. * Confirmed pregnancy * Contraindications to TMS and tDCS: metallic implant in the brain; medical devices implanted in the brain, heart pacemaker; cochlear implant; history of alcohol or drug abuse in the last 6 months; neurological pathologies; hx of head trauma or neurosurgery; decompensated systemic diseases and chronic inflammatory diseases (lupus, rheumatoid arthritis, Reiter's syndrome); uncompensated hypothyroidism; personal history of cancer, past or undergoing treatment. * Participants with diagnosis or recent contact with COVID will be excluded.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome fibromyalgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pain Fibromyalgia

Contacts and locations

Locations

  • Hospital de Clinicas de Porto Alegre

    Porto Alegre, Rio Grande do Sul, 90.450-120, Brazil

  • Hospital de clinicas de Porto Alegre

    Porto Alegre, Rio Grande do Sul, 9410000, Brazil

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