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Gut germs may turn your steak into heart risk

NCT ID NCT01731236

Knowledge-focused Sponsor: The Cleveland Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how bacteria in your gut break down certain nutrients from food, like carnitine (found in red meat) and choline (found in eggs). Researchers want to see if these gut bacteria produce substances that raise heart disease risk. About 100 healthy adults will provide blood samples to measure these effects. The goal is to understand the link between diet, gut bacteria, and heart health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2011

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men and women age 18 years or above. * Able to provide informed consent and comply with study protocol Exclusion Criteria: * Significant chronic illness or end-organ dysfunction, including known history of heart failure, renal failure, pulmonary disease, hematologic diseases or pregnancy. * Active infection or received antibiotics within 2 months of study enrollment * Use of Over-The-Counter (OTC) probiotic within past 2 months, or ingestion of yogurt within past 7 days * Chronic gastrointestinal disorders, or intolerance to probiotic therapy * Having undergone Bariatric procedures or surgeries such as gastric banding or bypass

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dietary modification

Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

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