Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Heart attack study halted: could conditioning the heart and arm help?

NCT ID NCT03155022

Disease control Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether using two types of 'ischemic conditioning' (brief cycles of blood flow restriction and release) could improve outcomes for people having a major heart attack. One method used a blood pressure cuff on the arm, the other used a balloon inside the heart artery during stent placement. The trial was stopped early, so we don't have clear answers on whether this combined approach helps patients recover better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ischemic conditioning (remote and intracoronary)
What this could lead to
If it had succeeded, this approach could have pointed toward a way to reduce heart damage and improve recovery after a heart attack.
What could go wrong
The trial was terminated early, so results are limited. It is unclear if the combined conditioning provides any real benefit, and the approach may not work for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

750 people

The number who actually took part.

Started

Apr 2018

Finished

Oct 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All (male and female) patients, aged over 18, * Presenting within 12 hours of the onset of chest pain, * For whom the clinical decision was made to treat with percutaneous coronary intervention (PCI), * ST segment elevation ≥ 0.2 mV in two contiguous ECG leads, * Written informed consent obtained or oral informed consent certified by a third party. Non inclusion Criteria: * Patients with cardiogenic shock, * Patients with uncontrolled (treated or untreated) hypertension (\> 180/110 mmHg), * Patients with loss of consciousness or confused, * Patients without health coverage, * Patient with any legal protection measure, * Female patients currently pregnant (oral diagnosis) or women of childbearing age who were not using contraception. Exclusion Criteria: Patients with main occlusion localized on : * LAD: distal or ostial segment, * Non dominant RCA / CX: mid or distal segment, * Dominant RCA / CX: distal segment, * Any other arteries apart LAD/CX/RCA; Patients with evidence of coronary collaterals to the risk region (Rentrop score ≥ 2); Patients with an opened (TIMI \> 1) culprit coronary artery on initial admission coronary angiography or a failed PCI (final TIMI=0).

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Myocardial infarction, acute are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

acute myocardial infarction myocardial infarction ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Myocardial infarction, acute

Contacts and locations

Locations

  • Algemeen Ziekenhuis Sint Jan

    Bruges, Belgium

  • CHU de Charleroi

    Charleroi, Belgium

  • Hopital Louis Pradel

    Bron, France

  • Universitair Ziekenhuis Antwerpen

    Edegem, Belgium

More trials for these conditions

Other studies related to the condition(s) this trial covers.