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Immune cells engineered to hunt brain tumors in spinal fluid

NCT ID NCT04661384

First seen Feb 21, 2026 · Last updated Apr 30, 2026 · Updated 12 times

Summary

This early-phase study tests whether specially engineered immune cells (CAR T cells) can safely target and destroy brain tumor cells that have spread to the lining of the brain and spinal cord. Ten adults with glioblastoma, ependymoma, or medulloblastoma will receive these cells. The main goal is to check for side effects and see if the treatment helps control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.