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Engineered immune cells take on lupus and kidney disease in new trial

NCT ID NCT07305116

First seen Jan 05, 2026 · Last updated Jun 02, 2026 · Updated 25 times

Summary

This early-stage study is testing a universal donor CAR T-cell therapy that targets two proteins (CD19 and BCMA) on immune cells that drive autoimmune diseases. The goal is to see if it is safe and can help control conditions like lupus, kidney disease, and vasculitis. About 15 participants will receive the treatment and be monitored for side effects and how long the cells last in the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital, Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310052, China

Conditions

The condition(s) this trial relates to.

anti-neutrophil cytoplasmic antibody-associated vasculitis autoimmune disease IgA glomerulonephritis nephrotic syndrome systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.