Vitamin d gel may fast-track braces: new trial
NCT ID NCT07200349
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether applying a Vitamin D gel (calcitriol) to one side of the upper jaw can speed up the movement of a canine tooth during orthodontic treatment. Twenty-two people aged 13 to 35 who need premolar extractions will participate. The gel is applied only on one side, and the other side serves as a comparison. The goal is to measure how much faster or farther the tooth moves with the gel.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 22 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2025
An estimate. Start dates often move.
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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13 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Presence of class I malocclusion requiring bilateral extraction of the maxillary first premolars and subsequent canine retraction. 2. Presence of class II malocclusion requiring bilateral extraction of the maxillary first premolars and subsequent canine retraction. 3. Age range between 13 and 35 years to include both adolescent and adult patients suitable for orthodontic treatment. 4. Presence of permanent dentition. 5. Good oral hygiene. Exclusion Criteria: 1. History of chronic systemic disease. 2. Presence of active gingival or periodontal disease. 3. Known allergy or hypersensitivity to vitamin D. 4. Pregnancy or lactation. 5. History of previous orthodontic treatment. 6. Presence of craniofacial anomalies affecting bone physiology.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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