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New 3D-Printed bone grafts show promise for dental implants
NCT ID NCT07163351
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested a new method to rebuild bone in the upper front jaw for dental implants. Researchers used custom-made donor bone blocks, designed with computer software, to support immediate implant placement. Twenty patients with bone loss from previous failed implants were treated. The study measured bone gain and implant success over 18 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- CAD/CAM allogenic bone block
- What this could lead to
- If successful, this approach could offer a more precise and less invasive way to rebuild jawbone for dental implants.
- What could go wrong
- This is a small, early study with only 20 participants and no comparison group. The long-term success and safety are still uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
20 people
The number who actually took part.
- Started
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Jan 2024
- Finished
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Jul 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged between 18 and 65 years. * Both sexes. * Patients presenting with anterior maxillary alveolar bone defects resulting from previous implant failure. * Systemically healthy individuals, classified as American Society of Anesthesiologists (ASA) physical status I or II. * Participants were either non-smokers or light smokers consuming fewer than 10 cigarettes per day. Exclusion Criteria: * Uncontrolled systemic conditions such as diabetes mellitus or osteoporosis. * Pregnant or breastfeeding at the time of recruitment. * Individuals with a history of head or neck radiation therapy. * Cases in which insufficient bone volume for implant placement persisted following augmentation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cairo University
Cairo, 12613, Egypt
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