CT scans could make bypass surgery smarter
NCT ID NCT03894423
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether advanced CT imaging can help doctors plan better coronary bypass surgery for 200 people with heart disease. Participants get a CT scan before and after surgery to measure blood flow changes. The goal is to improve surgical decisions and reduce chest pain, but the surgery itself is standard care, not a cure.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2019
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients scheduled to undergo coronary bypass graft surgery
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Planned elective CABG for coronary artery disease. * CABG is the primary indication for surgery (but may include treatment of mild-moderate valvular disease). * Age: ≥40 years. Exclusion Criteria: * Technical feasibility of the cardiac CT exams: redo-CABG, significant arrhythmia/mal-conduction, congenital conditions, severe valvular disease or cardiomyopathy (to the extent that the CT acquisition is technically challenged), inadequate understanding of the English language (to provide consent or follow instructions during the exams). * Overall safety: unstable clinical condition (clinical heart failure, unstable angina, myocardial infarction \<1 month prior). * Radiation risk: pregnancy (cannot be ruled out), body weight \>100kg. * CT contrast medium-related: known allergy, renal failure * Vasodilator related: known allergy, bronchial asthma requiring daily use of bronchodilators, Mobitz II or 3rd degree AV block, sick sinus node disease, clinically significant carotid artery narrowing, severe aortic stenosis or LVOT narrowing, systolic blood pressure below 90mmHg, (continued) use of dipyridamole or aminophylline. * Inability to provide informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Palo Alto Veterans Affaird Healthcare System
Palo Alto, California, 94304, United States
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Stanford University
Palo Alto, California, 94304, United States
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University of California San Diego
San Diego, California, 92093, United States
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