Your phone could help solve the mystery of burning mouth syndrome
NCT ID NCT05819697
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to better understand burning mouth syndrome by having 10 participants use a smartphone app to report their symptoms several times a day for 12 weeks. Researchers will also collect saliva samples to look for biological markers linked to the condition. The goal is to capture symptom patterns as they happen, rather than relying on memory, to improve future diagnosis and care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2023
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The target population will be patients who have been diagnosed with burning mouth syndrome by Oral Medicine specialists.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Individuals aged 18 years and older 2. Willing and able to provide informed consent 3. Have been diagnosed with BMS for at least three months by an Oral Medicine or other specialist 4. Willing to submit a saliva sample 5. Have continuous access to a smartphone Exclusion criteria: 1. In the opinion of the investigator, is unable or unlikely to comply fully with the study requirements or procedures for any reason (e.g. cognitive or physical impairment) 2. Prior head and neck radiation and/or chemotherapy 3. Medications that modulate or suppress the inflammatory system
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New mouthwash aims to soothe chronic mouth burning
- Laser or pill? new study tests two treatments for chronic mouth pain
- Could a simple splint cool the fire of burning mouth syndrome?
- New study seeks best remedy for chronic mouth burning
- New gel offers hope for chronic mouth burning