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New balloon could save dialysis patients from repeat surgeries

NCT ID NCT06639451

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 32 times

Summary

This study tests a special balloon coated with the drug paclitaxel to treat narrowed fistulas in people on hemodialysis. The balloon is inflated inside the blocked blood vessel to open it up and restore blood flow. Researchers are checking if this approach keeps the fistula working longer without needing another procedure. The trial enrolled 186 adults with mature fistulas who have been on stable dialysis.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Kansai Rosai Hospital

    Amagasaki, Hyōgo, Japan

  • Kishiwada Tokushukai Hospital

    Kishiwada, Osaka, Japan

  • Osaka Keisatsu Hospital

    Osaka, Osaka, Japan

  • Saiseikai Central Hospital

    Minato, Tokyo, Japan

  • Saitama Medical Center

    Kawagoe, Saitama, Japan

  • Shizuoka General Hospital

    Shizuoka, Shizuoka, Japan

  • Wakayama Medical University Hospital

    Wakayama, Wakayama, Japan

  • Yokohama Dai-ichi Hospital

    Yokohama, Kanagawa, Japan

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

paclitaxel-coated balloon catheter

What this could lead to

If successful, this could help people on dialysis maintain their fistula function longer, reducing the need for repeat procedures.

What could go wrong

This is a device study with no phase designation, so it's still early. The drug coating may cause local side effects, and results may not apply to all fistula types.

Conditions

The condition(s) this trial relates to.

congenital arteriovenous fistula

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.