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Breath training may unlock secrets of exercise fatigue

NCT ID NCT07103291

Knowledge-focused Sponsor: University of British Columbia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether 5 weeks of breathing endurance training using a special device can reduce breathlessness and improve exercise performance in healthy athletes. Researchers will compare real training to a sham version in 32 cyclists or triathletes. The goal is to understand how breathing exercises affect the brain and muscles, which could later help people with lung problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
respiratory muscle endurance training using the BreathWayBetter device
What this could lead to
If it works, this could help personalize breathing training for athletes and people with lung conditions, improving exercise tolerance.
What could go wrong
This is a small, early study in healthy adults only, so results may not apply to patients. The sham group may also show some benefit, making it hard to prove the real effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-55 years of age (inclusive) * Male or Female (biological sex) * Body mass index greater than 18 or less than 30 kg/m2 * Normal pulmonary function: FEV1/FVC \> 0.70 and FEV1 ≥ 80% * Able to read and understand English * Regularly trains and/or competes at a regional, national, or international level as a road cyclist or triathlete * Access to a device with the capability to download the Isocapnic app (Apple IOS or Google Play/Android) or the ability to use the Web Based application. Exclusion Criteria: * Currently smoke, vape, or use cannabis, or have a history of frequent smoking, vaping or cannabis use * History of, or current symptoms of cardiopulmonary (i.e., lung and/or heart) disease (excluding controlled asthma) * Heart problem; a serious infection within the body; a neuromuscular (nerve to muscle) or musculoskeletal (muscle, ligament and/or bone) disorder; or other health problem that will be made worse with exercise testing * Contraindications to exercise testing defined as anything that would prevent exercise under proper and safe conditions (e.g. a problem with the heart or lungs, muscle or bone injury, a serious infection) * Currently pregnant * Required to read and understand English due to the nature of the consent form and study materials, including questionnaires and training instructions, which are only available in English.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy adults

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • St. Paul's Hospital

    RECRUITING

    Vancouver, British Columbia, V6Z 1Y6, Canada

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