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Surgery-free breast cancer treatment tested in new trial

NCT ID NCT07245316

First seen Jan 04, 2026 · Last updated Jun 23, 2026 · Updated 20 times

Summary

This study is testing whether people with certain non-invasive or early breast conditions (like ductal carcinoma in situ) can safely skip surgery and instead take hormone-blocking medication. The goal is to see if this approach keeps cancer from coming back over five years. The trial will enroll 340 women whose biopsy shows hormone-sensitive, HER2-negative disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Samsung Medical Center

    Seoul, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

endocrine therapy (hormone-blocking medication)

What this could lead to

If successful, this could offer a way to manage certain early breast conditions with medication alone, avoiding the need for surgery.

What could go wrong

This is an early-stage study without a control group, so results may not confirm that skipping surgery is safe. There is a risk that cancer could return or progress without surgical removal.

Conditions

The condition(s) this trial relates to.

ductal breast carcinoma in situ

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.