Could a drug shrink Pre-Cancerous breast cells before surgery?
NCT ID NCT02928978
First seen Apr 24, 2026 · Last updated May 21, 2026 · Updated 5 times
Summary
This study tested the drug ruxolitinib in 84 people with high-risk breast conditions like DCIS or atypical hyperplasia. Half took ruxolitinib for about 15 days before surgery, and the other half took a placebo. The goal was to see if ruxolitinib could increase cell death in abnormal breast tissue, potentially lowering cancer risk.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Harris Health System - Smith Clinic
Houston, Texas, 77054, United States
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Indiana University Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, 46202, United States
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Montefiore Medical Center
The Bronx, New York, 10461, United States
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O'Quinn Medical Tower - McNair Campus; Dan L Duncan Comprehensive Cancer Center
Houston, Texas, 77054, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, 37232, United States
Conditions
Explore the condition pages connected to this study.