Scientists dig into tumor DNA to predict breast cancer survival
NCT ID NCT07630558
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study analyzed stored tumor samples and medical records from nearly 1,900 Greek women who had surgery for early breast cancer. Researchers looked at genetic changes and protein markers in the tumors to see how they relate to breast cancer subtypes and long-term survival. The goal is to better understand which tumor features matter most for patient outcomes, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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1,891 people
The number who actually took part.
- Started
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Jan 1997
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study includes tumors from patients with operable breast cancer of intermediate or high risk of relapse, according to St.Gallen criteria, treated with dose-dense sequential adjuvant chemotherapy with epirubicin, cyclophosphamide, taxane (only a certain group did not include a taxane) and "intensified" CMF.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women with histologically confirmed epithelial breast cancer * Age \>18 years * Pathological stage * Eastern Cooperative Oncology Group performance status 0-1 * Normal cardiac function and adequate bone marrow, hepatic and renal function.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Study site
Athens, Greece
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Other studies related to the condition(s) this trial covers.
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