Hellenic Cooperative Oncology Group
Clinical trials sponsored by Hellenic Cooperative Oncology Group, explained in plain language.
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Real-world review of two powerful breast cancer drugs shows promise for advanced disease
Disease control CompletedThis study looked at how safe and effective two targeted drugs, trastuzumab deruxtecan and sacituzumab govitecan, are for people with advanced breast cancer. Researchers reviewed medical records of 312 patients who had already tried other treatments. The goal was to see side effe…
Sponsor: Hellenic Cooperative Oncology Group • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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Massive data review reveals how breast cancer patients fare on intensive chemo
Knowledge-focused CompletedThis study analyzed information from over 5,000 people with early-stage breast cancer who received a specific type of chemotherapy called dose-dense sequential chemotherapy. The goal was to see how long they lived without the cancer coming back and what side effects they had. Thi…
Sponsor: Hellenic Cooperative Oncology Group • Aim: Knowledge-focused
Last updated May 26, 2026 03:10 UTC
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Immune cells in breast tumors may predict Long-Term survival
Knowledge-focused CompletedThis study looked at immune cells (called TILs and CD8+ T cells) in tumor samples from over 3,600 women with early-stage breast cancer who had chemotherapy after surgery. The goal was to see if these cells are linked to how long patients live without the cancer coming back. The f…
Sponsor: Hellenic Cooperative Oncology Group • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC
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Immune clues in ovarian tumors: a new way to predict survival?
Knowledge-focused CompletedThis study looked at tumor samples from 687 women with advanced high-grade serous ovarian cancer to see if certain immune cells (like T cells and plasma cells) are linked to how well patients do. Researchers checked for structures called tertiary lymphoid structures and a protein…
Sponsor: Hellenic Cooperative Oncology Group • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Scientists Re-Analyze old tumor samples to unlock secrets of HER2-Low breast cancer
Knowledge-focused CompletedThis study looked at tissue samples from 2751 women with early breast cancer who had already been treated with chemotherapy. The goal was to compare tumors with very low HER2 levels (HER2-low) to those with none (HER2-zero) to see if they behave differently. Researchers hope this…
Sponsor: Hellenic Cooperative Oncology Group • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC