Hellenic Cooperative Oncology Group
Clinical trials sponsored by Hellenic Cooperative Oncology Group, explained in plain language.
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Real-world review of two powerful breast cancer drugs shows promise for advanced disease
Disease control CompletedThis study looked at how safe and effective two targeted drugs, trastuzumab deruxtecan and sacituzumab govitecan, are for people with advanced breast cancer. Researchers reviewed medical records of 312 patients who had already tried other treatments. The goal was to see side effe…
Sponsor: Hellenic Cooperative Oncology Group • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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Scientists Re-Analyze old samples to unlock secrets of HER2-Low breast cancer
Knowledge-focused CompletedThis study looked at tissue samples from 2751 women with early breast cancer who had already been treated with chemotherapy. The goal was to see if cancers with low levels of HER2 protein (HER2-low) are different from those with no HER2 (HER2-zero). By comparing these groups, res…
Sponsor: Hellenic Cooperative Oncology Group • Aim: Knowledge-focused
Last updated May 16, 2026 23:34 UTC
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Immune cell analysis in 3,646 breast cancer patients reveals clues for future treatment
Knowledge-focused CompletedThis study looked at immune cells called TILs and CD8+ T cells in tumor samples from 3,646 women with early-stage breast cancer who had chemotherapy after surgery. The goal was to see if these cells are linked to how long patients live or if their cancer comes back. The findings …
Sponsor: Hellenic Cooperative Oncology Group • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Immune clues in ovarian tumors may predict survival
Knowledge-focused CompletedThis study examined tumor samples from 687 women with advanced high-grade serous ovarian cancer who received standard chemotherapy. Researchers looked for different types of immune cells, such as T cells and plasma cells, to see if their presence was linked to how well patients d…
Sponsor: Hellenic Cooperative Oncology Group • Aim: Knowledge-focused
Last updated May 12, 2026 13:44 UTC
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Massive data review reveals how well Dose-Dense chemo works for early breast cancer
Knowledge-focused CompletedThis study combined data from over 5,300 early-stage breast cancer patients to see how well dose-dense sequential chemotherapy works over the long term. Researchers looked at how long patients stayed cancer-free and overall survival, as well as side effects. The goal was to bette…
Sponsor: Hellenic Cooperative Oncology Group • Aim: Knowledge-focused
Last updated May 07, 2026 18:40 UTC