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New hope for kids with deadly brain tumors: trial tests Immune-Boosting drug

NCT ID NCT04049669

Summary

This study is testing whether adding an immunotherapy drug called indoximod to standard chemotherapy and radiation can better control aggressive brain tumors in children and young adults. It is for patients aged 3 to 21 with specific types of progressive brain cancer or newly diagnosed DIPG. The goal is to see if blocking a natural immune-suppressing pathway helps the body's own defenses fight the tumor more effectively alongside standard treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Augusta University, Georgia Cancer Center

    Augusta, Georgia, 30912, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Emory University, Children's Heathcare of Atlanta

    Druid Hills, Georgia, 30322, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.