New hope for kids with tough brain cancers: trial tests Immune-Boosting drug

NCT ID NCT04049669

Summary

This study is testing whether adding an immunotherapy drug called indoximod to standard chemotherapy and radiation can better control aggressive brain tumors in children and young adults. It is for patients aged 3 to 21 with certain progressive brain cancers or a newly diagnosed, hard-to-treat brainstem tumor called DIPG. The goal is to see if boosting the body's immune response helps slow tumor growth and improve survival compared to standard treatment alone.

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Contacts and locations

Locations

  • Augusta University, Georgia Cancer Center

    Augusta, Georgia, 30912, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Emory University, Children's Heathcare of Atlanta

    Druid Hills, Georgia, 30322, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.