Could brain zaps curb anorexia's compulsive grip?
NCT ID NCT06138782
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can reduce compulsive behaviors in people with anorexia nervosa. Twenty participants will receive multiple sessions of rTMS targeting a brain region linked to obsessive-compulsive disorder. The goal is to identify brain network changes that might lead to new treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Repetitive transcranial magnetic stimulation (rTMS)
- What this could lead to
- If successful, this could point toward a new treatment option for anorexia nervosa by targeting brain circuits linked to compulsive behaviors.
- What could go wrong
- This is a very small, early-stage study with only 20 participants. It is designed to understand brain networks, not to prove a treatment works. The results may not lead to a therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Oct 2023
- Expected to finish
-
Sep 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
16 to 75 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * outpatients * ages 16 - 75 for Aim 2 * meets Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for AN * stable on chronic psychotropic medications for 4 weeks prior to the study and agreeable to continue throughout the study * participants may continue to take medications and record daily usage throughout the study * capacity to provide informed consent * ability to tolerate clinical study procedures * successfully complete the screening forms without any contraindications Exclusion Criteria: * Psychiatric: schizophrenia, bipolar disorder, prior psychosurgery, prior electroconvulsive therapy (ECT) * Neurologic: severe neurocognitive disorder, seizure disorder, certain structural brain lesions (e.g., intracranial mass lesions, hydrocephalus, sequelae of meningitis) * TMS contraindications: implanted device; presence of metal in the head, including eyes and ears (excluding dental implants); certain tics; medications or systemic illness that predispose seizure risk * Subjects with an unstable physical, systemic, or metabolic disorder (e.g., unstable hypertension) * Females who are pregnant or nursing * Inability to complete the research study
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Anorexia nervosa are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of California, San Francisco
San Francisco, California, 94107, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can the Brain's Information-Integration process explain Anorexia's grip?
- Can a pudding snack reveal how the brain misreads the stomach?
- Could the gut microbiome hold clues to eating disorder recovery?
- Can a parent support group help teens with both autism and anorexia?
- Lab-Grown brain cells could unlock Anorexia's secrets
- Can science unlock the secrets of the naturally lean?