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Brain zapping study seeks to unlock eating secrets in anorexia

NCT ID NCT05918835

Knowledge-focused Sponsor: New York State Psychiatric Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times

Summary

This study uses a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to explore how it changes food choices and brain activity in people with anorexia nervosa. Researchers will give a single session of rTMS to 72 women aged 18-30 who are hospitalized for anorexia. The goal is to understand the brain mechanisms behind restrictive eating, not to treat the disorder directly.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS)
What this could lead to
If successful, this study could reveal how brain stimulation affects food choices in anorexia, pointing toward future treatments that target eating behaviors.
What could go wrong
This is a small, early-stage study with only 72 participants, all female and in a hospital setting. Results may not apply to everyone with anorexia, and the stimulation is given just once, so any effects are temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 72 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2023

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * DSM-5 Diagnosis of Anorexia Nervosa * Age 18-35 years * Female * Right-handed * Body Mass Index (BMI) ≥ 16.0 * Voluntarily admitted to inpatient eating disorders unit at NYSPI * Competent to provide informed consent * English-speaking * Medically stable Exclusion Criteria: * High risk of suicide * Current substance use disorder or other co- morbid psychiatric condition requiring specialized treatment (e.g., psychosis) * Diagnosis of major medical or neurological problem or taking medication that significantly increases risk for seizure or affects interpretation of findings (e.g., unstable hypertension, seizure disorder) * Food restrictions (e.g., allergies) which impact greater than 30% of food choice task's choice options * Indwelling ferromagnetic metallic object (e.g., pacemaker, pump), non- removable metal jewelry, medicinal patch or recent metallic ink tattoo * History of seizure * Diagnosis of epilepsy, stroke, multiple sclerosis, traumatic brain injury, Alzheimer's and other neurodegenerative diseases, meningoencephalitis or intracerebral abscess, or parenchymal or leptomeningeal cancers * Prior exposure to TMS * Pregnancy * Currently breast-feeding * Significant claustrophobia * Implanted devices or stimulators * Hearing loss (e.g., currently undergoing treatment with ototoxic medications or those with cochlear implants)

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Conditions

The condition(s) this trial relates to.

anorexia nervosa Feeding and Eating Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anorexia nervosa

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • New York State Psychiatric Institute

    RECRUITING

    New York, New York, 10032, United States

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