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Healthy volunteers help map new drug's brain activity

NCT ID NCT05470101

First seen Sep 30, 2025 · Last updated Jun 11, 2026 · Updated 36 times

Summary

This early-stage study tested a single dose of the experimental drug ITI-333 in 12 healthy adults aged 18-45. Researchers used PET scans to see how much of the drug reached and attached to a specific brain receptor (5-HT2A). The main goals were to measure receptor binding, drug levels in the blood, and safety. This study does not treat any disease but helps understand how the drug works in the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Clinical Site 1

    St Louis, Missouri, 63110, United States

  • Clinical Site 2

    Creve Coeur, Missouri, 63141, United States

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.