Healthy volunteers help map new drug's brain activity

NCT ID NCT05470101

First seen Sep 30, 2025 · Last updated Jun 11, 2026 · Updated 36 times

Summary

This early-stage study tested a single dose of the experimental drug ITI-333 in 12 healthy adults aged 18-45. Researchers used PET scans to see how much of the drug reached and attached to a specific brain receptor (5-HT2A). The main goals were to measure receptor binding, drug levels in the blood, and safety. This study does not treat any disease but helps understand how the drug works in the body.

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Contacts and locations

Locations

  • Clinical Site 1

    St Louis, Missouri, 63110, United States

  • Clinical Site 2

    Creve Coeur, Missouri, 63141, United States

Conditions

Explore the condition pages connected to this study.