Healthy volunteers help map brain effects of experimental drug ITI-333

NCT ID NCT05470101

First seen Sep 30, 2025 · Last updated Apr 28, 2026 · Updated 27 times

Summary

This early-stage study tested a single dose of the experimental drug ITI-333 in 12 healthy adults aged 18-45. Researchers used PET brain scans to see how much of the drug attached to a specific brain receptor (5-HT2A) and checked safety and drug levels in the blood. The goal was to gather basic information, not to treat any disease.

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Contacts and locations

Locations

  • Clinical Site 1

    St Louis, Missouri, 63110, United States

  • Clinical Site 2

    Creve Coeur, Missouri, 63141, United States

Conditions

Explore the condition pages connected to this study.