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Massive study tests yearly brain scans for lung cancer patients

NCT ID NCT07646041

Knowledge-focused Sponsor: Samsung Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study analyzed health records from over 229,000 people with newly diagnosed lung cancer in Korea to see if getting a brain MRI every year helps find cancer that has spread to the brain. The goal was to learn whether these scans catch brain metastases earlier, when they might be easier to treat, and whether this leads to better survival. The study did not involve any new treatments—it simply looked back at existing data to understand the value of routine brain imaging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

229,323 people

The number who actually took part.

Started

Jan 2012

Finished

Dec 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study will include patients with newly diagnosed lung cancer identified from linked nationwide Korean data sources, including the Korean National Health Insurance Service database, the Health Insurance Review and Assessment Service database, and the Korea Central Cancer Registry. Patients diagnosed with lung cancer between 2012 and 2021 will be eligible. Patients with evidence of brain metastasis before or at the time of lung cancer diagnosis will be excluded.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Patients will be eligible if they have newly diagnosed lung cancer between 2012 and 2021 Exclusion Criteria: * Prior brain MRI within the preceding within 1 year * Incident brain metastasis before trial entry. * Recent neurologic symptoms, emergency department use, hospital admission, neurologic consultation, or prescriptions for dexamethasone, mannitol, levetiracetam, or valproate within prespecified time windows around the MRI date.

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Conditions

The condition(s) this trial relates to.

brain cancer lung cancer lung neoplasm metastatic malignant neoplasm in the brain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain metastasases Lung cancer MRI Surveillance

More trials for these conditions

Other studies related to the condition(s) this trial covers.